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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '810499378d016e4f55f85ee729257559ad61a7d6999acb5ee631c2bdc22a1267' 
  AND token = '61BA1rJw5/jGpofd7e4oeW9jFrxfQQInhoosBLkyQEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}