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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd33f8595266dbd05c52de76f557d839acf343a28ca04f4bcb3d9cad8201a4e3d' 
  AND token = 'U5AEuIEQsDTvUZuLOg5KKYQEdNeqnhmfUZlHsyPaLt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}