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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38730b067e8571ded4e674f9b7fcd647db0d2288201e843069d13b57f39133d1' 
  AND token = '7oK3S5APWpwbfjzdB9Ek0ClCNXmXn18WkvBC3O/0W9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}