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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff001fa3c66a5f202a0d0b7fa137ac5e46bb6f6b84d508d094d3aa5dcc74cd35' 
  AND token = 'LuoqRB+SDVn3hXRR/XVz20MAOO7HUk2djGs8ExBeO4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}