SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '434c54574162ab58edd9fb97f56f5946932fcbdaad6983c466c78ab357d8ada7' 
  AND token = 'BiSPVAXPRlQlxwuNjPSKQQDApC2EQg+vW9msPy6AMk8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00076

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}