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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3043377f4d81b7e9884cb9d246ec312bcda2e55b0c7208ce78244088e85d5ed' 
  AND token = 'YqSqkiKbxz2C3ZWiLlNDtSi+0qFQuu7mFEDG5AfjvYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}