SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4cd0dfa53e9c4ef822324d20fb18b6bf256e1c6d1f5a2600cd1e6f75ee7d398' 
  AND token = 'fzfk0cnLtg22VWqJJXJHeH6TQ7lP7EAxofWINUW/Gfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}