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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2968ed5acb372ded6229ece9046534da99ca245e96c9de0c1dba9cb7bcafedb2' 
  AND token = 'zq1RZxJ3/F2FF6OLTqtED52D60BgeKJFDcyG2AN3Xm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}