SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70c123d1bc27058594b95659bddbf2e5ee8a637828afba055d566f681da462f0' 
  AND token = '8VRw6WlNQt6ypRM1fmRRwgXO+dUYSvNrXMopi0XlMyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}