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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e95413b9bc705cacd6ab0129dfc259bf1f7f15928f94c2ed96477201d07d7ba' 
  AND token = 'TrJZiImHz9QNaDj7ZiL93Dq1NYo9ucHWZviYaMZVCF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}