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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c70325745a3b6a33588e04f1172dcbc50690070177e08aa47210fd33c7e9660' 
  AND token = 'I4R7lTMTMYg0qiVPBfB+r5MwVkVXWdz/nDQqeiB/KBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}