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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70150c048ae1fe43fcf2a7824822d0aa3fc8c5fe998a73377288f9605a477d2a' 
  AND token = 'ERHHOxYYNmFghDe428Q0YB2wrSjGPz1b/DSi5Xh7RpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}