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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0300f074e1cccf0d96a6f1557bed23d60b1b2a46bb64933ab40b848c347d54ec' 
  AND token = 'p0IIYvpbGCzIUEyaxLp7v5quVEyN5QUJE51bOtBXqIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}