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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ddf4f6d947157d6f9c07cab90396a4c892c9430fa8ce6c06bf7c3e48e1f1906' 
  AND token = 'wvTLiRMxDZHz9y63gfS470qC2RBrsnfdaKcSB6jDmvI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}