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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12b86f6cb492f1d86a2cb663c83e57f0e2308062cc11bbb5a3e22ca357cc8923' 
  AND token = 'Echu9xIBtj4cjKqL2MPSslB5mnGG6m/WhmtCqYT7LqU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}