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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db063b193544f0ced157588b5159125e717f688b3f1edcf3fddb4985d67cce5d' 
  AND token = '+EMslZWpmVwN5I8rTx6aeRexYmJSS0hQAxHzS7zZz8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}