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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35ffe8b5ee60bf987976fe84eb1ace3d338382a7e88837596e37e540acd6e644' 
  AND token = 'R3pY2xBcBHRwi76Xoag1aY9CTVakMdsDeK5STokyJSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}