SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bd9aa0b0f7b72256b269d8ec0aa13299261454aefadf27c5f26efdbf16478f6' 
  AND token = 'awnIFPXrgmUkNVv+zAyQuED97rvDxVLKOjq028ctroY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}