SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6acbd9e6b3cff24e9e1615e0f492fd2b81fc88d25eb71dd649e66096ab20f16' 
  AND token = 'NqHz0NYx51UiS5LxGs+rVnRXbyhSQewmLpEe99YcjsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}