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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ecc9d1a621dd89fb7aac15bd6f4042f3fcab5fa331048ac22cfa64c9ee28543' 
  AND token = 'F6F24QiVai0uDtbXzW5UkMi+zxyDI82+jTvG9C+nJ00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}