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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '068f7d7fba8f34ebb2aaa6753645e9f0e1772739632e264b24d1d21de15aab86' 
  AND token = 'pAl4touxBq9r5tZ/EYPnstEIMHS9kQF3b3J/oow9hzY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}