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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e1c3030c0eaceae76aacc90d5a23475e4e788ad07c7acddb19babf2bb2de5aa' 
  AND token = 'NM/ZzM/tbCMO49a+GCK/vxhLU3k5Rd3dP6eA4cQzMFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}