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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21b6e09f35cac57223fc9bda4186d7a25a912ecf8600252fa0b8f7f7b357d9d7' 
  AND token = '4Ks3o21WOFPZOVth5nf8imv5oskuw+UWkEvDvmn4Gtw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}