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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c3ca0d8f8a555067c13aa2484f48d2c82521a0e0b84fc3b1eee247334773574' 
  AND token = '+N4HjPqFpLe+k9sUksPJbfHrt0YJpk/c3XSkVKsQhZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}