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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d2be56b4160256830fa7abdadd390d358d501a2edcab1d99a98d51ece957487' 
  AND token = 'Wgta1n1kEdKJ9juag3IrjePW4U2bzRF5UbKiLznKLjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}