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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08bda6b25854bf2d50c16e7d9eb25365277cf8bd3a9c50e74343e2bc55d14cc8' 
  AND token = 'En1eaSG03uoOAldBZSCy3p3Gwa5lGzZVzkSVyOYVGkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}