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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10212bc59db63bf439f9810a68d7b5104edad67b7fca3b8e00de01d0c1d49e48' 
  AND token = '4U1Qw7Bh2LABh4Gdmq73UEpeJWmik3W/vCeWvPRx4tI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}