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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e8f4133024095f752d66acedf9b3c9b213fae2fe4c0173b7f48bfee718f086e' 
  AND token = '2xGYlJDttDPxdRR7arYeONeOv4R/E+Rym3ZsjHyVyO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}