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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee321241a12f44b9f87061ac7ecdecbdecba93d91473f816d96d3c6aec221382' 
  AND token = 'd6cps9zsPx7CGIpmwxqpHSA7l5fvtd3C+ZKGJT1UrFY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}