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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fc621556c47736255523de95b9e8666654527231fb9c0e5f386c4b584a130ef' 
  AND token = '8dwAxI2Xrwq3YXBa+sPiVJYApiHfe51rU9N+TTpkpTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}