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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef3c38990eed29aea9a5cb38d6e3082da25f78aad8c0dfc360801f3493895764' 
  AND token = '3JjL5WpIUM7tbI4qSkWHsZxiHa8bGnSdRdKVI6N9lUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}