SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e04499708b77e923db08130fd8ac3209d2e3c4268cac0d6ab95723ad28d897e9' 
  AND token = 'zylmXoMkUIWR+pM7KsE3yz5zZ6JrjeBYgWUAjyYLzFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}