SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c452e3a96be4c64284bd4bcee7a715f65e281642e27ec27d7fa9282fd18a40ff' 
  AND token = 'sQHn+fpFugqzd191hvc4XtqhYO4loPHm1Jw6AieBF08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}