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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '616ddd80cf7a472dea80516beed0d9eed093cd7f05025a0bb5cba1987a1c7ec9' 
  AND token = 'QPB88LmBBBocZa+4S5lx4yrwXHyZ+sxD7zPKR2LIwGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}