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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e11eea5441088bd98d0431f78d89d8508a693a89b2320e6ec46b3dd773b5fc4' 
  AND token = 'u2K8idC1xPtLUVmhNAPqVUy0VY7GLZNJrwL42gEMVPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}