SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0ed64e0acf4024348b6888107b81e484e56d1470f4dc3ba220bfcdce532507d' 
  AND token = 'ZSdwgG/AxLfPV86x8KjWdgx1raWxeGVD5xJ7KzH/UrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}