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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5333d422278773130475415ce80c334616deccbc3baf93017fc82e3dc2821417' 
  AND token = '1X1i0hhGWVF0QdVvYEvruGzAEDVE8CnUp7Fu2mzHW4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}