SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5773176cf359ab19e5d232a9a6e62d18628bfe603740f56e32b42d11cb9e6c3' 
  AND token = '1zkIVKi5Gc2XVyuFRElR76X2Vq1bfFCTPFWcdqzdKvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}