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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '585c5b3f14618a2525299dfd0498047ed9e5d65d03339da5a15fbf885b4d7c9f' 
  AND token = 'ZlkouFX6crB4/hOoAKY9GYomPFTzA74r4Dd4DZPBXks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}