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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fa081b5c1c85cdfd4cdb36f06d380b109d39f8240a5cf1fceb19a434f750efb' 
  AND token = '9YHMNKoZrfs0LNuFjg8+UQkg8FtDz+tMp9/R4JFQxT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}