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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0021171dcd7bf4463dccd354af527060f6dce57de0a68747bcecb84e46c5e6eb' 
  AND token = '+j5Ux0k41nV2OAPosOb/LaqPeZZ0nLRBt9US9qRyTIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}