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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e0929046dcdccbff612d6f378e931a4e4af32a841433e3493e42f3436c3cb78' 
  AND token = '+qDyATxC4SUXhdh2ANI/9R737NgZ2cA5/s1VcyKSOEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}