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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '639918e4a159de46554a03b0fb5855412d71c44053b45d08d6083f324a8843c8' 
  AND token = 'QN8P3m8LIxsCDdB1A1ZpcRDQK+wRlHrjp8kt1UVrdgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00086

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}