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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cfd7c6f5ecf0d5436d53f7823cd6483cc65830099d71e3cbdfdaa340355fd7e' 
  AND token = '1HEUEHMkghcjN+7G+dmmFaK0OgxEz+biU3sZTv9eA6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}