SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0353ff3cad4dc3375b1dd631baaf447c5ad33acdac1e5aaa3ac9c0ef283ad62a' 
  AND token = 'OXLoIk3zkD6cudbRwKEWjIoIDsYZRskcrh6RdG0YHQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}