SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4651056475df1d5ccd13030eeaee207961b1e612b6883885de95b54be747fc85' 
  AND token = 'sxCdIOtHgD7uSW8zOZSTAh7JsT1Tij7dvuiP7eAmXJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}