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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2176f21ce89d660dffb194b45ecaca178f4dca00d1c740bb97314b8bac1fd3db' 
  AND token = 'Ew5FodRaeZllg3e7G++l72zwLNAJSrAYo5zrV7SxDPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}