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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a73d499397d2b53568d5b996d60bf7a1dd81fd037deb0710da9b6447073acdec' 
  AND token = 'xocXFqH9z3iAt8VwqXAJB/X8W6D/8LlvLm6bwtWpjow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}