SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '140ab3ebec70a3d7b161e851020ff4bfcf56549dbff1acf3b8e96ce11858c775' 
  AND token = 'DG0chwr4aRywd1TKSUMM8O5Af7GIr+ptg8wGkDyDB0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}