SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2826225cce6f3ec74cb4fb87889a2f3772ad531e291d4f64bd6b38b36f99c0f' 
  AND token = 'P+cu6gPL15Q6FjFZeOiQEPew5mqNjN74qB72RWxXgE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}